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Crohn's Disease EAT Todd's Story Ulcerative Colitis

Heal Your Gut – Easily, and Free, I Know, Sounds Too Good To Be True, Read On…..

This is exciting!

I WISH this was around when I first got sick

When I was running to the bathroom daily

When I kept a spare pair of underwear in my glove compartment

Seriously, I use to need that

I had to learn how to eat the hard way

For you, check it out. It’s EASY

A study to test how the Paleo AIP diet affects Inflammatory Bowel Disease

Funded by Scripps Hospital

your health insurance

And their Clinic and Research Institute counterpart

You KNOW how your diet affects your symptoms

Eat the wrong food, feel shitty

BLOATED

GASSY

CONSTIPATED

Texting your friend: “Hey! Sorry, I can’t make it out tonight, feeling funky”

That sucks, I know, I’ve been there

But what IS the wrong food?

The first food I ever eliminated was lettuce

My then GI Doctor told me roughage was difficult to digest

That didn’t work for me

I then eliminated dairy

That also didn’t work for me

Low Residue Diet?

Also didn’t work

There’s an endless amount of diets to try

Pescatrian, Vegan, SCD, GAPS, Paleo AIP

It’s OVERWHELMING

Sticking with it – not easy!

When I was a Health Coach I noticed something

Group coaching works

It’s more affordable

You’re with friends

You have a mentor

Daily inspiration

A gradual approach to add healing foods to your diet

In an unintimidating way

Nervous?

Scared?

Overwhelmed?

Heard how tough it is to start?

No worries!

This healing approach isn’t difficult

It’s done in a safe, supportive environment

Basically, they hold your hand almost guaranteeing success

No, they can’t eat the food for you

But they will be there with you every step of the way

Todd inspired his GI Doctor, Dr. Gauree G. Konijeti, MD, MPH to do the study, and now it’s funded! Go Todd!

If Scripps Clinic takes your insurance, you’re good to go!

Unfortunately, MediCal patients are not covered

The study is limited to 20 participants, and enrollment is underway

If you’re interested in learning more, email Crystal Sanchez at Sanchez.Crystal@scrippshealth.org, and let her know you learned about this on One Great Gut

If you’re not in the San Diego Area, or are unable to take part in the study, Check out the The Alternative Auto-Immune Cookbook, or SAD to AIP in SIX online course you can enroll in from wherever you are in the world.

If you want to learn more about the study, here’s an email Dr. Konijeti sent her colleagues

From: Konijeti, Gauree MD
Sent: Tuesday, June 28, 2016 4:55 PM
Subject: Autoimmune Protocol Diet Study for IBD- enrolling now

Hi everyone,

Here are the details on our prospective study examining the Efficacy and Feasibility of the Autoimmune Protocol Diet for IBD.

What is it? A 12 week study, starts Sept. 1, 2016 for all 20 participants. Let’s see how the autoimmune protocol diet affects symptoms, microbiome, and inflammation in IBD.

–       No cost to the patient for participation

–       Participants will have a registered dietician and certified health coach follow them via email and private/secret Facebook group. We are collaborating with a team from this website (AutoImmunePaleo – Group Coaching)

–       We will monitor labs, stool microbiome, and IBD disease activity during study.

–       I will see them in clinic before and after the study, but will not intervene on their IBD unless their clinical status changes during the study.

–       I will take care of ordering labs (blood, stool) during study

–       If possible, we want to get biopsies for RNA expression analysis in August (before study) and after study (last week November/1st week December). Endoscopy can be done by their own GI doc or me. GI doc just needs to collected 2 extra biopsies to put in a designated vial (everything will be there and ready at time of procedure)

–       Participants will otherwise follow-up with their own GI doc for IBD care

If you have interested patients, please have them email Sanchez.Crystal@scrippshealth.org

Inclusion Criteria:

  • Age 18 and over
  • Comfortable with using internet and Facebook
  • Mild-moderate Crohn’s disease or ulcerative colitis

o    CD: Harvey Bradshaw Index ≥ 5

o    UC: partial Mayo score ≥ 3

o    Endoscopic or radiographic inflammation

o    If you have an interested patient and not sure whether they qualify, just email Crystal Sanchez and me. Don’t worry about the indices!

  • Patients can be on any IBD med, need to keep doses stable during 12 week study. Steroids can be adjusted as needed.

Exclusion Criteria

  • Celiac disease, active and untreated infection, stoma or J pouch, planned bowel surgery, need for antibiotics
  • Pregnancy or nursing

Any questions, let me know. Thanks!

Gauree

 Ps – More details, if you are interested…

 Research Summary:

The most important goals of therapy for inflammatory bowel disease (IBD) are to achieve clinical remission —patient is feeling well, off steroids, and has a good quality of life—and endoscopic remission—focused primarily on the absence of ulcerations on endoscopic evaluation. Achievement of these goals results in sustained remission, and decreased risks of complications such as cancer, surgery, and hospitalization. However, remission has proven difficult to achieve due of suboptimal responses to immunosuppressive therapy, especially in patients with moderate-to-severe disease. Therefore, research is increasingly focusing on the gut microbiome, environmental exposures and dietary factors that can be modified to influence disease risk and course. With respect to diet, a Western diet, high in refined carbohydrates, omega-6 fatty acids, and saturated fat, and low in fiber, vitamins, and generally nutrient dense foods, has been associated with an increased risk of IBD, possibly related to dysbiosis. Studies have demonstrated decreases in gut microbial Bacteroides, Lactobacillus, Bifidobacterium, andFirmicutes among patients with IBD, with associated changes in microbial function including decrease in short chain fatty acids and amino acid biosynthesis, and increases in sulfate transport, oxidative stress, and secretion of toxins. Controversy exists as to whether dysbiosis identified in IBD patients provoked or resulted from their IBD. Unfortunately, we have limited data to guide the use of nutritional therapy as either primary or adjunctive treatment for IBD, and it can prove challenging to implement in the setting of altered anatomy, comorbid conditions, and patient compliance. Therefore there is an important need to study diet as a therapy for IBD. Here, we propose a novel study to evaluate the feasibility and efficacy of the autoimmune protocol (AIP) diet in patients with CD and UC.

Specific Aims:

1) To evaluate the effect of the AIP diet on clinical and endoscopic disease activity for CD and UC

2) To examine changes in fecal microbiome populations during the AIP diet transition and maintenance phases

3) To characterize changes in RNA expression from intestinal mucosal biopsy specimens from prior to diet initiation to end of the study.

gauree-konijeti--300x400

Gauree G. Konijeti, MD, MPH

Director, Inflammatory Bowel Disease Program

Division of Gastroenterology, Scripps Clinic

KL2 Scholar, The Scripps Research Institute

La Jolla, California

Office: 858-554-8880

Fax: 858-554-8065

 

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