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Malibu Microbiome Meeting

UPDATE: Postponed until August 22nd and 23rd

One of our volunteer advisers has been planning something special behind the scenes, and it’s finally around the corner…a continuing medical education(CME) event for both practitioners and patients.

Dr. Sabine Hazen MD, CEO of Ventura Clinical Trials, Malibu Specialty Center and Progenabiome is putting together a meeting of the minds.

Physicians, government, and industry share the latest in microbiome research, discoveries, and news on the gut flora and its role in dis-ease and healing potential.

Malibu Microbiome Meeting Dr. Borody Fecal Transplant FMT

Malibu Microbiome Meeting Conference
March 28 and 29 at Pepperdine University in the beautiful warm beach city of Malibu California.


Patients, friends and family members who want to learn from the best of the best, tap into a collaborative supportive community and learn about evidence-based Integrative research and treatment options that normally take months or years to reach you while having a healthy fun time – yes this is for you.

Practitioners who want to connect with like-minded colleagues while learning about the latest clinical research, standards, and applications to elevate your toolbox and practice to a new level and be able to help more patients – yes this is for you

Researchers who want to connect with like-minded colleagues while learning about the latest findings to bring back to your clinic and further advance research which goes along with our Mission to HAMAPASAP – Help As Many As Possible As Soon As Possible

CME’s available

Because the World Needs Superheroes, These Doctors Work to Advance Medical Research and Save Lives

Expert Speakers Include:

Dr. Thomas Borody – from Centre for Digestive Diseases in Australia
Dr. Neil Stollman – UCSF / East Bay Center for Digestive Health
Dr. Sabine Hazen Progenabiome
Dr. Alex Khoruts – University of Minnesota
Dr. Colleen Kelly – Brown University
Dr. Yinghong Wang – MD Anderson Cancer Center
Dr. Paul Feurstadt – Yale School Of Medicine
Dr. Howard Young – National Institutes of Health(NIH)
Dr. Jessica Allegretti – Harvard Medical School
Dr. Sahil Khanna – Mayo Clinic

Christian Hundley / © TripSavvy

– Topics Include IBD Crohn’s, Colitis, Alzheimers, Autism, C.Diff, Cancer, Children, UTI and other applications

– Catering by Malibu Farms providing fresh, organic and local farm-to-table food

– Hootenanny For Healing with The Malibu Guitar Festival Saturday night w/ Live Music. Dinner. Drinks. Dancing. Fun Benefiting Microbiome Research Foundation @ Private Malibu Estate with Live Music from Brandon Jenner, The Kenneth Brian Band, and a special guest appearance we’re not yet at the liberty to announce 😉

Yes, that Jenner. Brandon’s parents are U.S. track and field Olympian Caitlyn Jenner and actress Linda Thompson. He is the brother of Brody Jenner, half-brother of Kendall, Kylie, and Burton Jenner, and Cassandra Marino. Brandon is now the ex-stepbrother of Kourtney, Kim, Khloé, and Rob Kardashian,

– Vendor Booths including Diagnostic Solutions Laboratory – Creators of GI-MAP and CytoDX. (Patients: You may now order these tests on your own here)

– Affordable pricing and for additional savings use code onegreatgut for 25% off + they have been kind to donate back to the One Great Gut Foundation for every ticket purchased using that code. So if you decide to attend you not only will receive the most advanced and up to date information about microbiome research and applications you’ll help us achieve our mission which is to help 10M Integratively Thrive with IBD,. Thrive Physically, Mentally, Emotionally and Spiritually.

NOTE:  One Great Gut does not promote or advocate for the clinical practices of the speakers as we are personally not familiar with their treatment recommendations, and more importantly, the results they are able to provide to their patients. We are promoting the Malibu Microbiome Meeting as a meaningful event to attend for up to the date scientific information and research. If you are looking for a vetted qualified practitioner you may consider the One Great Gut Network to help you Thrive. Many of the practitioners not only have IBD themselves but have fixed it, no longer suffer and now help other’s achieve those same results.

More on some of the speakers:

Professor Thomas Borody, founded the Centre for Digestive Diseases (CDD) in 1984 after a distinguished career with leading hospitals including St Vincent’s in Sydney and the Mayo Clinic in the USA.
He is a world-renowned leader in the clinical microbiota dating back to 1988 when he started performing what is now called Fecal Microbiota Transplantation (FMT).
The CDD has published 220+ scientific papers, treated 78,000+ patients, has 14+ inventions in market or trials, and Professor Borody holds over 150 patents in areas such as: treatment of Helicobacter pylori, Crohn’s disease, bowel lavage, IBS and FMT.


• medical degree: NYU School of Medicine
• residency: Columbia University – College of Physicians and Surgeons
• chief residency (Internal Medicine): Columbia University – College of Physicians and Surgeons
• fellowship (gastroenterology & advanced therapeutic endoscopy): University of Miami School of Medicine
An expert in C difficile infection and fecal transplantation, diverticular disease and H pylori, Dr. Stollman has published his work in journals such as Lancet, Gastroenterology, the American Journal of Gastroenterology, and Gastrointestinal Endoscopy.
He has served on the American Gastroenterological Association Research and Clinical Guidelines Committees, the American College of Gastroenterology Educational Affairs, Patient Care, and Credentialing Committees and the Editorial Advisory Board of Gastrointestinal Endoscopy.
Dr. Stollman is also a Fellow of the American Gastroenterological Association (AGA) and the American College of Gastroenterology (ACG). He is currently the Chairman of the ACG Board of Governors.
He is currently an Associate Clinical Professor of Medicine at UCSF, Chief of the Division of Gastroenterology at Alta Bates Summit Medical Center in Oakland, and prior Chief of Gastroenterology at the Miami VA Medical Center and San Francisco General Hospital.

• medical degree: Weill Medical College of Cornell University
• residency: New York Presbyterian Hospital
• fellowship: Montefiore Medical Center-Albert Einstein College of Medicine
Throughout Dr. Feuerstadt’s career he has been involved in research and other academic pursuits. His research focuses include fecal microbiota transplantation, Clostridioides difficile infection, irritable bowel syndrome and ischemic bowel disorders. He has presented his research extensively and has authored and co-authored many manuscripts and textbook chapters.
Another passion of Dr. Feuerstadt’s is teaching, frequently giving lectures locally, regionally, nationally and internationally and mentoring the fellows in the Division of Digestive Disease at Yale-New Haven Hospital where he is an Assistant Clinical Professor of Medicine.
We are honored to have Dr. Feuerstadt speaking on “Challenges Around Clinical Trials in C.difficile” at the Malibu Microbiome Meeting on March 28-29, 2020


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Accidental Fear or Valid reporting? Risk of New IBD Rises for Patients Treated With Etanercept

The Center for Biosimilars today published an article that concluded that there is a fearful risk of being diagnosed with IBD Crohn’s or Colitis for those currently being treated with Etanercept.

Respectfully, I believe this study is incomplete and does not tell the full story. Though I don’t currently have access to the full study, just the Wiley Online Library Summary and the Center for Biosimilars article, until Lifestyle and Diet are factored into these studies I believe they do not tell the complete story.  20 years of clinical and cost outcomes from Integrative Medicine* have demonstrated the following results:

60% Decrease in hospital admissions
59% Reduction in hospital days
62% Savings in Outpatient surgeries and procedures
85% Reduction in Pharmaceutical costs
*Data provided by Patient-centered integrative medicine Independent Practice Association (IPA) per Advanced Medicine Integration Group, L.P. (AMI)

With the efficacy of leverage of using Integrative Medicine Lifestyle and Dietary changes, and the rise of it’s usage I believe a study like this is incomplete and may be unintentionally promoting accidental fear. What do you think?

Combined with the recent news that the United States Congress is grappling with tainted Chinese drugs, baffled by lack of FDA oversight in the U.S. pharmaceutical supply chain*. Remember when lead paint in children’s toys were a problem? That’s nothing compared to my concern to FDA Approved drugs potentially containing unwanted excipients.

As shown by the patients I interviewed during the Crohn’s And Colitis Summit who believe they are now cured of IBD Crohn’s and Colitis it’s becoming increasingly apparent for all of us to pay attention to our Physical, Mental, Emotional and Spiritual healing and growth.

Etanercept is a biopharmaceutical that treats autoimmune diseases by interfering with tumor necrosis factor by acting as a TNF inhibitor. It has U.S. F.D.A. approval to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis.

They state that while anti-tumor necrosis factor (anti-TNF) drugs are effective at treating a range of inflammatory diseases, some limited data suggest that they may, paradoxically, result in a higher risk of developing other de novo inflammatory conditions.

It’s worth mentioning that anti-TNF drugs are not the only drugs available to those with inflammatory diseases. Recently the United States FDA approved Stelara for ulcerative colitis. It’s also important to note that there are different inflammatory markers in the body. TNFa is only one of those markers. When my TNFa was low, I failed Remicade. Though this was the recommendation of my then specialist Doctors, it seemed apparent to me that I would fail Remicade, and subsequently, I did. This resulted in a horrific QOL(Quality of Life) and a very small regretful view of the world and shitty symptoms.  In hindsight, I should never have tried Remicade knowing that my TNFa was within the normal range. If you are wondering what your inflammatory markers look like I recommend ordering a test from this page: IBD Crohn’s Colitis test you can order from home.

Recently, Danish researchers sought to assess whether there is a link between anti-TNF therapy and the development of inflammatory bowel disease (IBD).1 Using nationwide Danish registries, the group examined data for all patients with rheumatoid arthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis, pemphigus, alopecia areata, and vitiligo who were enrolled between 1994 and 2017. Anti-TNF agents were introduced in Denmark in 2004, and there were 17,018 individuals who had been exposed to anti-TNF drugs and 63,308 who had not been exposed.

Overall, 7344 patients were treated with infliximab, 9072 were treated with etanercept, and 8355 were treated with adalimumab. Fewer patients were treated with golimumab (n = 1973) or certolizumab pegol (n = 2503). Overall, 34.1% of patients were exposed to 2 anti-TNF drugs, and 16.7% were exposed to 3 or more.

The researchers found that patients treated with etanercept had a significant increase in the risk of developing new Crohn disease (CD), with an adjusted hazard ratio (HR) of 2.0 (95% CI, 0.8-2.2). The adjusted HRs for developing CD were 1.3 (95% CI, 0.8-2.22) for infliximab and 1.2 (95% CI, 0.8-1.8) for adalimumab. There was no statistically significant increased risk for new CD with golimumab or certolizumab pegol.

Additionally, patients treated with etanercept had a significant increase in the risk for developing new ulcerative colitis (UC), with an adjusted HR of 2.0 (95% CI, 1.5-2.8). The adjusted HRs for developing new UC were 1.0 (95% CI, 0.6-1.6) for infliximab and 0.6 (95% CI, 0.3-1.0) for adalimumab. Again, there was no statistically significant increased risk for new UC with golimumab or certolizumab pegol.

According to the authors, “This study firmly establishes the risk of developing de novo IBD while on anti‐TNFα agents, particularly with etanercept.”

In a letter linked to the publication, a separate group of authors from the centers in China noted that a different TNF binding pattern may be responsible for the increased risk of new IBD with etanercept versus other anti-TNFs.2

Etanercept binds to 2 of 3 sites of the TNF molecule, while infliximab binds to all 3, they explain. Additionally, unlike infliximab or adalimumab, etanercept does not bind to peripheral blood cells and lamina propria mononuclear cells derived from patients with IBD. Infliximab and etanercept also have different effects on cytokine production of T lymphocytes, “possibly inducing IBD in genetically predisposed patients,” say the authors, adding that more research into IBD-triggering pathways is warranted.

Lessons Learned:

If you’re unsure which pro-inflammatory markers are high in your body, consider your options here: IBD Crohn’s Colitis test you can order from home. Doctor approval is direct from the companies listed, you do not need to obtain prior approval from your personal Doctor, which can lead to unwanted delays, or being denied to have the blood test you wish to see the results of for your body to make the most educated decision for your health.

Any purchase from the lab test companies on that page, or the below links will allow the One Great Gut Foundation to get closer to meeting our initiatives which help you Thrive with IBD Crohn’s and Colitis. So you can invest in your health and build a healthier world through our initiatives, at the same time. Thrive Physically, Mentally, Emotionally and Spiritually.

Monitoring your health. The Crohn’s Disease Activity Index (CDAI) and the Simple Clinical Colitis Activity Index (SCCAI) are useful tools to consider using.  They access disease activity in Crohn’s and Ulcerative Colitis. For children, consider the Pediatric Crohn’s Disease Activity Index(PCDAI ) or Pediatric Ulcerative Colitis Activity Index (PUCAI).

Lab Tests to Consider

TH1 TH2 Cytokine Test – Basic
For those with a confirmed autoimmune condition, the Th1 Th2 test is possibly the most important test. The test points out imbalances in the immune system by looking at cytokines, proteins that the immune system relies on to communicate. Bad communication results in complications for those with autoimmune conditions. The information this test provides helps your doctor develop a strong and effective treatment plan for you, especially when seeking alternative medicine support.

The immune system works like a seesaw. On one side you have Th1 cytokines that initiate the first line of defense. On the other side, you have Th2 cytokines that help produce antibodies to protect you from future invasions. However, when one side goes up, the other side goes down. This can contribute to a weak immune system and potentially promote autoimmune issues. Running this test will help to understand where the imbalance is. Because certain botanicals used in natural medicine can boost Th1 cytokines and Th2 cytokines, this test can help you and your doctor develop an effective plan to help balance a weak immune system and turn the volume down on autoimmune attacks.

TH1 TH2 TH17 Cytokine Test – Advanced aka CytoDX
This test is more detailed than the above with readings including

  • Inflammatory Cytokines- Th1
    • INF Gamma: Th1
    • IL-1 beta: Th1
    • IL-2: Th1
    • IL-6: Th1 and Th2
    • IL-7: Weak Th1
    • IL-8: Weak Th1
    • IL-12 p70: Th1
    • IL-17A: Th17
    • IL-18: Weak Th1
    • TNF alpha- Th1
  • Anti-Inflammatory Cytokines- Th2
    • IL-4: Th2
    • IL-5: Th2
    • IL-10: T-regulatory cells
    • IL-13: Th2
    • IL-15: Weak Th2

TH17 Test
New studies show that an increase in a particular type of white blood cell, called Th17 cells, can trigger and determine the severity of autoimmune conditions. Monitoring Th17 levels can help you and your doctor better treat the condition.

Basic CD4 CD8 Ratio Test
The CD4 CD8 ratio profile helps assess the immune system in detail. This test is crucial for patients who are suspected of having a compromised immune system as seen in autoimmune conditions and HIV.

Any purchase from the lab test companies above using the above links will allow the One Great Gut Foundation to get closer to meeting our initiatives which help you Thrive with IBD Crohn’s and Colitis. So you can invest in your health and build a healthier world through our initiatives, at the same time. Thrive Physically, Mentally, Emotionally and Spiritually.

1. Korzenik J, Larsen MD, Nielsen J, Kjeldsen J, Norgard BM. Increased risk of developing Crohn’s disease or ulcerative colitis in 17,018 patients while under treatment with anti‐TNFα agents, particularly etanercept, for autoimmune diseases other than inflammatory bowel disease. Aliment Pharmacol Ther. 2019;50(3):289-294. doi: 10.1111/apt.15370.

2. Dai C, Jian M, Sun MJ. Letter: increased risk of developing Crohn’s disease or ulcerative colitis in 17 018 patients while under treatment with anti‐TNFα agents, particularly etanercept, for autoimmune diseases other than IBD. Aliment Pharmacol Ther. 2019;50(7):834-835. doi: 10.1111/apt.15460.

3. AP&T – Alimentary Pharmacology and Therapeutics – Increased risk of developing Crohn’s disease or ulcerative colitis in 17 018 patients while under treatment with anti‐TNFα agents, particularly etanercept, for autoimmune diseases other than inflammatory bowel disease – Joshua Korzenik Michael Due Larsen Jan Nielsen Jens Kjeldsen Bente Mertz Nørgård First published: 02 July 2019  The Handling Editor for the article was Professor Richard Gearry, and it was accepted for publication after full peer‐review. Funding information: University of Odense Hospital Free Research Foundation.

* Newsweek October 2019 Congress grappling with tainted Chinese Drugs, is baffled by lack of FDA oversight in U.S. Pharmaceutical supply chain by Blake Dodge